Journal article icon

Journal article

The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides.

Abstract:

The crystal structure refinement of the synthetic dodecamer d(CGCGAASSCGCG), where S = 4'-thio-2'-deoxythymidine, has converged at R=0.201 for 2605 reflections with F > 2sigma(F) in the resolution range 8.0-2.4 A for a model consisting of the dodecamer duplex and 66 water molecules. A comparison of its structure with that of the native dodecamer d(CGCGAATTCGCG) has revealed that the major differences between the two structures is a change in the conformation of the sugar-phosphate backbone...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/nar/24.5.951

Authors


Journal:
Nucleic acids research More from this journal
Volume:
24
Issue:
5
Pages:
951-961
Publication date:
1996-03-01
DOI:
EISSN:
1362-4962
ISSN:
0305-1048
Language:
English
Keywords:
Pubs id:
pubs:400285
UUID:
uuid:b82878f4-11c7-4a6c-ad58-0d6c4dc427ec
Local pid:
pubs:400285
Source identifiers:
400285
Deposit date:
2013-11-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP