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Ion channels in EEG: isolating channel dysfunction in NMDA receptor antibody encephalitis

Abstract:

Neurological and psychiatric practice frequently lack diagnostic probes that can assess mechanisms of neuronal communication non-invasively in humans. In N-methyl-D-aspartate (NMDA) receptor antibody encephalitis, functional molecular assays are particularly important given the presence of NMDA antibodies in healthy populations, the multifarious symptomology and the lack of radiological signs. Recent advances in biophysical modelling techniques suggest that inferring cellular-level properties...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/brain/awy107

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
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Academy of Medical Sciences More from this funder
Wellcome Trust More from this funder
University of Zurich More from this funder
René and Susanne Braginsky Foundation More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Brain Journal website
Volume:
141
Issue:
6
Pages:
1691-1702
Publication date:
2018-04-30
Acceptance date:
2018-02-22
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Pubs id:
pubs:846189
URN:
uri:b82611af-8eb9-4910-911b-a556eddb656f
UUID:
uuid:b82611af-8eb9-4910-911b-a556eddb656f
Local pid:
pubs:846189

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