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B cells with immune-regulating function in transplantation

Abstract:

In transplantation, the contribution of B cells to the rejection or acceptance of the allograft is a topic of major interest. The presence of donor-specific antibodies in transplant recipients is often associated with decreased graft function and rejection, clearly indicating a pathogenetic role of B cells in transplantation. However, data from studies in humans and rodents suggest that under certain conditions, B cells have the capacity to control or regulate the immune response to a transpl...

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Publisher copy:
10.1038/nrneph.2014.80
Publisher:
Nature Publishing Group
Journal:
Nature Reviews Nephrology More from this journal
Volume:
10
Issue:
7
Pages:
389-397
Publication date:
2014-01-01
DOI:
EISSN:
1759-507X
ISSN:
1759-5061
Language:
English
Pubs id:
pubs:476896
UUID:
uuid:b80e8678-4140-41ac-be99-153b12c4dbe6
Local pid:
pubs:476896
Source identifiers:
476896
Deposit date:
2014-08-14

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