Journal article
Cross-Coupling of [2-Aryl-1,1,2,2-tetrafluoroethyl](trimethyl)silanes with Aryl Halides.
- Abstract:
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The synthesis of arylCF2CF2SiMe3 and their reactivity in cross-coupling reactions with aryl iodides and aryl bromides to afford a range of 1,1,2,2-tetrafluoro-1,2-arylethanes is reported. The use of pyridine as an alternative to phenanthroline, and the ability to carry out the reaction at 60 °C or room temperature are the key features of this Cu-Ag mediated cross-coupling methodology. The chemistry is compatible with (hetero)aryl halides, offering a platfor...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
-
(Accepted manuscript, pdf, 966.3KB)
-
- Publisher copy:
- 10.1021/acs.orglett.5b01510
Authors
Funding
Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- ACS Publications Publisher's website
- Journal:
- Organic letters Journal website
- Volume:
- 17
- Issue:
- 14
- Pages:
- 3466-3469
- Publication date:
- 2015-07-01
- Acceptance date:
- 2015-05-23
- DOI:
- EISSN:
-
1523-7052
- ISSN:
-
1523-7060
- Pmid:
-
26126930
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:531741
- UUID:
-
uuid:b806f755-afdf-4f8d-8dc4-8738922e91b3
- Local pid:
- pubs:531741
- Source identifiers:
-
531741
- Deposit date:
- 2017-08-08
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2015
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from ACS Publications at DOI:10.1021/acs.orglett.5b01510
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