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Journal article

A panel of kallikrein markers can reduce unnecessary biopsy for prostate cancer: data from the European Randomized Study of Prostate Cancer Screening in Goteborg, Sweden.

Abstract:

BACKGROUND: Prostate-specific antigen (PSA) is widely used to detect prostate cancer. The low positive predictive value of elevated PSA results in large numbers of unnecessary prostate biopsies. We set out to determine whether a multivariable model including four kallikrein forms (total, free, and intact PSA, and human kallikrein 2 (hK2)) could predict prostate biopsy outcome in previously unscreened men with elevated total PSA. METHODS: The study cohort comprised 740 men in Göteborg, Sweden...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/1741-7015-6-19

Authors


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Swedish Cancer Society More from this funder
More from this funder
Grant:
LSHC-CT-2004-503011
Fundación Federico SA. More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC medicine Journal website
Volume:
6
Issue:
1
Article number:
19
Publication date:
2008-01-01
DOI:
EISSN:
1741-7015
ISSN:
1741-7015
Source identifiers:
365930
Language:
English
Keywords:
UUID:
uuid:b804df47-1875-484b-baa8-c6bd83823447
Local pid:
pubs:365930
Deposit date:
2013-11-16

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