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Current and emerging therapies for PNETs in patients with or without MEN1

Abstract:

Pancreatic neuroendocrine tumours (PNETs) might occur as a non-familial isolated endocrinopathy or as part of a complex hereditary syndrome, such as multiple endocrine neoplasia type 1 (MEN1). MEN1 is an autosomal dominant disorder characterized by the combined occurrence of PNETs with tumours of the parathyroids and anterior pituitary. Treatments for primary PNETs include surgery. Treatments for non-resectable PNETs and metastases include biotherapy (for example, somatostatin analogues, inhi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1038/nrendo.2018.3

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More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; OCDEM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; OCDEM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; OCDEM
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Funding agency for:
Thakker, RV
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Funding agency for:
Thakker, RV
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Reviews Endocrinology Journal website
Volume:
14
Issue:
2018
Pages:
246-227
Publication date:
2018-02-16
Acceptance date:
2018-01-05
DOI:
EISSN:
1759-5037
ISSN:
1759-5029
Pubs id:
pubs:825706
URN:
uri:b80217c5-153e-4991-8d8e-edc02af83faf
UUID:
uuid:b80217c5-153e-4991-8d8e-edc02af83faf
Local pid:
pubs:825706

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