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Journal article

Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis.

Abstract:

Interferon (IFN)-gamma plays an important role in the pathogenesis of sepsis. Production of IFN-gamma is stimulated by synergistic effects of interleukin (IL)-18, IL-12, and IL-15. To investigate the regulation of IFN-gamma production during severe gram-negative infection, the plasma concentrations of IFN-gamma, IL-18, IL-12, and IL-15 were measured in 83 patients with suspected melioidosis. The diagnosis was confirmed in 62 patients, 31 of whom had blood cultures positive for Burkholderia ps...

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Publication status:
Published

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Publisher copy:
10.1086/315155

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Journal:
Journal of infectious diseases
Volume:
180
Issue:
6
Pages:
1878-1885
Publication date:
1999-12-01
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Source identifiers:
37292
Language:
English
Keywords:
Pubs id:
pubs:37292
UUID:
uuid:b7e6df85-0200-4ab7-91d4-3292e72dd7da
Local pid:
pubs:37292
Deposit date:
2012-12-19

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