- Abstract:
-
Experimental data (e.g., genetic lineage and cell population studies) on intestinal crypts reveal that regulatory features of crypt behavior, such as control via morphogen gradients, are remarkably well conserved among numerous organisms (e.g., from mouse and rat to human) and throughout the different regions of the small and large intestines. In this article, we construct a partial differential equation model of a single colonic crypt that describes the spatial distribution of Wnt pathway pr...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.bpj.2010.05.016
-
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- Journal:
- Biophysical journal
- Volume:
- 99
- Issue:
- 3
- Pages:
- 716-725
- Publication date:
- 2010-08-05
- DOI:
- EISSN:
-
1542-0086
- ISSN:
-
0006-3495
- URN:
-
uuid:b7dc1da5-b560-442f-ba20-f2470564633c
- Source identifiers:
-
67590
- Local pid:
- pubs:67590
- Language:
- English
- Keywords:
- Copyright date:
- 2010
Journal article
Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts.
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