Journal article
Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts.
- Abstract:
-
Experimental data (e.g., genetic lineage and cell population studies) on intestinal crypts reveal that regulatory features of crypt behavior, such as control via morphogen gradients, are remarkably well conserved among numerous organisms (e.g., from mouse and rat to human) and throughout the different regions of the small and large intestines. In this article, we construct a partial differential equation model of a single colonic crypt that describes the spatial distribution of Wnt pathway pr...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.bpj.2010.05.016
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Authors
Bibliographic Details
- Journal:
- Biophysical journal
- Volume:
- 99
- Issue:
- 3
- Pages:
- 716-725
- Publication date:
- 2010-08-01
- DOI:
- EISSN:
-
1542-0086
- ISSN:
-
0006-3495
- Source identifiers:
-
67590
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:67590
- UUID:
-
uuid:b7dc1da5-b560-442f-ba20-f2470564633c
- Local pid:
- pubs:67590
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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