Journal article icon

Journal article

Evaluation of the effect of chronic antidepressant treatment on neurokinin-1 receptor expression in the rat brain.

Abstract:

Clinically effective antidepressants are thought to exert their therapeutic effects by facilitating central monoamine neurotransmission. However, recent data showing that neurokinin-1 receptor (NK1R) antagonists have antidepressant properties in both animal and clinical studies raise the possibility that classical antidepressants may also influence NK1R expression in the brain. To test this hypothesis, rats were treated with desipramine, paroxetine, venlafaxine, tranylcypromine or vehicle for...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
Neuropharmacology
Volume:
46
Issue:
8
Pages:
1177-1183
Publication date:
2004-06-01
DOI:
EISSN:
1873-7064
ISSN:
0028-3908
Source identifiers:
139419
Language:
English
Keywords:
Pubs id:
pubs:139419
UUID:
uuid:b7d6eb74-79bd-484d-b764-c3729558af8a
Local pid:
pubs:139419
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP