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CD4(+) T cell responses to cytomegalovirus in early life: a prospective birth cohort study.

Abstract:

We compared cytomegalovirus (CMV)-specific interferon-gamma (IFN-gamma), interleukin 2 (IL-2), and CD154 CD4(+) T cell responses of infants to those from chronically infected adults and from children aged 4-5 years. Magnitudes of the responses were similar, although coexpression of IFN-gamma plus CD154 occurred more than coexpression of IFN-gamma plus IL-2 or IL-2 plus CD154. Responses remained constant during infancy, although the proportion of IFN-gamma-producing cells increased from infanc...

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Publication status:
Published

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Publisher copy:
10.1086/527418

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Journal:
Journal of infectious diseases More from this journal
Volume:
197
Issue:
5
Pages:
658-662
Publication date:
2008-03-01
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Language:
English
Keywords:
Pubs id:
pubs:176618
UUID:
uuid:b7caa624-a2e6-4654-9c30-22e4615df997
Local pid:
pubs:176618
Source identifiers:
176618
Deposit date:
2012-12-19

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