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Developing the BALANCE trail--the role of the pilot study and start-up phase.

Abstract:

OBJECTIVES: The initial design of the BALANCE (Bipolar Affective disorder: Lithium / ANtiConvulsant Comparative Evaluation) Trial of maintenance treatment for bipolar disorder was based on the experience of previous trials in bipolar disorder and psychiatry and on the methods developed for large randomized trials in other areas of medicine. This report describes the adaptations to the initial design and trial procedures following the initial phases of the study. The rationale for the trial a...

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Publication status:
Published

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Journal:
Bipolar disorders
Volume:
6
Issue:
1
Pages:
26-31
Publication date:
2004-02-01
DOI:
EISSN:
1399-5618
ISSN:
1398-5647
Source identifiers:
98000
Language:
English
Keywords:
Pubs id:
pubs:98000
UUID:
uuid:b7c6ab80-2d85-4a7c-be67-1f99096a0b14
Local pid:
pubs:98000
Deposit date:
2012-12-19

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