Thesis
Aspects of modelling solid tumours
- Abstract:
-
This thesis considers aspects of modelling solid tumours. We begin by considering the common assumption that nutrient or drug concentrations in avascular tumour spheroids are radially symmetric. We derive a simple Poisson equation for biomolecular diffusion into an avascular tumour, but with highly oscillatory boundary conditions due to the surrounding capillary network. We find that the assumption of radial symmetry is legitimate for biomolecules that are taken up in sufficient quantities...
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Authors
Contributors
+ Maini, P
Division:
MPLS
Department:
Mathematical Institute
Role:
Supervisor
+ Gaffney, E
Division:
MPLS
Department:
Mathematical Institute
Role:
Supervisor
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Schofield, J
Bibliographic Details
- Publication date:
- 2010
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:b7c50880-ed03-451e-9841-209f2de6a982
- Local pid:
- ora:12145
- Deposit date:
- 2015-08-13
Terms of use
- Copyright holder:
- Schofield, J
- Copyright date:
- 2010
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