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Journal article

Sensitivity of multiphase pseudocontinuous arterial spin labelling (MP pCASL) magnetic resonance imaging for measuring brain and tumour blood flow in mice

Abstract:

Brain and tumour blood flow can be measured noninvasively using arterial spin labelling (ASL) magnetic resonance imaging (MRI), but reliable quantification in mouse models remains difficult. Pseudocontinuous ASL (pCASL) is recommended as the clinical standard for ASL and can be improved using multiphase labelling (MP pCASL). The aim of this study was to optimise and validate MP pCASL MRI for cerebral blood flow (CBF) measurement in mice and to assess its sensitivity to tumour perfusion. Follo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1155/2018/4580919

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
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Publisher:
Hindawi Publishing Corporation Publisher's website
Journal:
Contrast Media and Molecular Imaging Journal website
Volume:
2018
Article number:
4580919
Publication date:
2018-11-07
Acceptance date:
2018-09-26
DOI:
EISSN:
1555-4317
ISSN:
1555-4309
Pubs id:
pubs:922564
UUID:
uuid:b7c4df20-2931-4562-b126-d36897631a39
Local pid:
pubs:922564
Deposit date:
2018-10-01

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