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Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer.

Abstract:

BACKGROUND: Standard biomarker testing of a single macroscopic disease site is unlikely to be sufficient because of tumor heterogeneity. A focus on examining global biomarker expression or activity, particularly in microscopic residual chemotherapy-resistant disease, is needed for the appropriate selection of targeted therapies. This study was aimed at establishing a technique for the assessment of biomarkers of ovarian cancer peritoneal spread. METHODS: An in-house developed fluorescent imag...

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Publication status:
Published

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Publisher copy:
10.1002/cncr.29029

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Publisher:
John Wiley and Sons Inc.
Journal:
Cancer
Volume:
121
Issue:
2
Pages:
202-213
Publication date:
2015-01-05
DOI:
EISSN:
1097-0142
ISSN:
0008-543X
URN:
uuid:b7affb44-1dc9-46c4-afa7-f31e3cb7fa6f
Source identifiers:
484035
Local pid:
pubs:484035

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