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m6A modification of non-coding RNA and the control of mammalian gene expression

Abstract:

The biology of non-coding RNA (ncRNA) and the regulation of mammalian gene expression is a rapidly expanding field. In this review, we consider how recent advances in technology, enabling the precise mapping of modifications to RNA transcripts, has provided new opportunities to dissect post-transcriptional gene regulation. With this has come the realisation that in the absence of translation, the modification of ncRNAs may play a fundamental role in their regu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bbagrm.2018.12.002

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Oxford college:
Pembroke College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
ORCID:
0000-0003-4838-2653
Publisher:
Elsevier
Journal:
Biochimica et biophysica acta. Gene regulatory mechanisms More from this journal
Volume:
1862
Issue:
3
Pages:
310-318
Publication date:
2018-12-11
Acceptance date:
2018-12-07
DOI:
EISSN:
1876-4320
ISSN:
1874-9399
Pmid:
30550772
Language:
English
Keywords:
Pubs id:
pubs:954462
UUID:
uuid:b7a24516-ba36-4fbd-bc6b-e66b6c00941e
Local pid:
pubs:954462
Source identifiers:
954462
Deposit date:
2019-03-01

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