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Strategies to improve detection and management of human parechovirus infection in young infants

Abstract:

Human parechovirus infections are the second most common cause of viral meningitis in children. These infections are most frequently seen in infants younger than 90 days. Clinical manifestations include encephalitis, meningitis, myocarditis, and sepsis, which can lead to serious neurodevelopmental sequelae in young infants. Molecular techniques, including PCR assays, are the preferred diagnostic methods and have contributed to an increase in reported cases, along with an increasing awareness ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/s1473-3099(18)30288-3

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
ORCID:
0000-0003-3658-7635
Harvala, H More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Oxford college:
St Cross College
ORCID:
0000-0001-7361-719X
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Publisher:
Elsevier Publisher's website
Journal:
Lancet Infectious Diseases Journal website
Volume:
19
Issue:
2
Pages:
e51-e58
Publication date:
2018-10-12
Acceptance date:
2018-04-27
DOI:
EISSN:
1474-4457
ISSN:
1473-3099
Pubs id:
pubs:928835
URN:
uri:b78ef0e1-3e60-433d-9ec8-6bdeed7a793a
UUID:
uuid:b78ef0e1-3e60-433d-9ec8-6bdeed7a793a
Local pid:
pubs:928835
Language:
English

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