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Relationship between in vitro chromosomal radiosensitivity of peripheral blood lymphocytes and the expression of normal tissue damage following radiotherapy for breast cancer.

Abstract:

BACKGROUND AND PURPOSE: There is a need for rapid and reliable tests for the prediction of normal tissue responses to radiotherapy, as this could lead to individualization of patient radiotherapy schedules and thus improvements in the therapeutic ratio. Because the use of cultured fibroblasts is too slow to be practicable in a clinical setting, we evaluated the predictive role of assays of lymphocyte chromosomal radiosensitivity in patients having radiotherapy for breast cancer. MATERIALS AN...

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Publication status:
Published

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Authors


Barber, JB More by this author
Burrill, W More by this author
Spreadborough, AR More by this author
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Journal:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Volume:
55
Issue:
2
Pages:
179-186
Publication date:
2000-05-05
DOI:
EISSN:
1879-0887
ISSN:
0167-8140
URN:
uuid:b779755c-b550-4822-a51f-015fc8a209ea
Source identifiers:
131034
Local pid:
pubs:131034

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