Journal article icon

Journal article

IE63-specific T-cell responses associate with control of subclinical varicella zoster virus reactivation in individuals with malignancies.

Abstract:

BACKGROUND: Reactivation of the varicella zoster virus (VZV) is more common in patients with malignancies; however, the molecular and cellular mechanisms underlying this susceptibility are unclear. METHODS: Using ex vivo interferon-gamma ELISpot assays, we set out to analyse VZV-specific immune responses in a large cohort of patients with malignancies. RESULTS: We observed that patients with malignancies had impaired VZV-specific T-cell responses, particularly in those with haematological mal...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/sj.bjc.6605542

Authors


Malavige, GN More by this author
Rohanachandra, LT More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Expand authors...
Journal:
British journal of cancer
Volume:
102
Issue:
4
Pages:
727-730
Publication date:
2010-02-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:b776bf0d-2bd4-4039-85f4-a8f1b02df6f0
Source identifiers:
46162
Local pid:
pubs:46162

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP