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Journal article

Metabolic conversion as a pre-receptor control mechanism for lipophilic hormones.

Abstract:

The majority of physiological effects mediated by steroids, retinoids and thyroids is accomplished by binding to members of the nuclear receptor superfamily of ligand activated transcription factors. The complex specific effects of lipid hormones depend not only on receptor expression, distribution and interactions, but also on the availability and metabolic conversion of the hormone itself. The cell-specific metabolic activation of inactive hormone precursors introduces a further level of ho...

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Publication status:
Published

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Authors


Abrahmsen, L More by this author
Oppermann, U More by this author
Journal:
European journal of biochemistry / FEBS
Volume:
268
Issue:
15
Pages:
4113-4125
Publication date:
2001-08-05
DOI:
EISSN:
1432-1033
ISSN:
0014-2956
URN:
uuid:b75b307f-1b52-42ad-8699-e5029cb616e2
Source identifiers:
108711
Local pid:
pubs:108711

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