In studies exploring the effects of HCMV infection on immune system ageing ('immunosenescence'), after organ transplantation or in other settings, HCMV-specific T-cell responses are often assessed with respect to purportedly 'immunodominant' protein subunits. However, the response structure in terms of recognized antigens and response hierarchies (architecture) is not well understood and actual correlates of immune protection are not known.We explored the distribution of T-cell response sizes...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's version
- Copyright holder:
- Sylwester et al.
- Copyright date:
- © 2016 The Authors. Published by Elsevier Ireland Ltd. This is an open access article under the CC BY-NC-ND license.
A new perspective of the structural complexity of HCMV-specific T-cell responses (Revision 1).
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