Journal article icon

Journal article

A new perspective of the structural complexity of HCMV-specific T-cell responses (Revision 1).

Abstract:

In studies exploring the effects of HCMV infection on immune system ageing ('immunosenescence'), after organ transplantation or in other settings, HCMV-specific T-cell responses are often assessed with respect to purportedly 'immunodominant' protein subunits. However, the response structure in terms of recognized antigens and response hierarchies (architecture) is not well understood and actual correlates of immune protection are not known.We explored the distribution of T-cell response sizes...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1016/j.mad.2016.03.002

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author
Expand authors...
More from this funder
Grant:
R01-AI47606, RO1-AI21640, MO1-RR000334, P51-RR00163
Publisher:
Elsevier Publisher's website
Journal:
Mechanisms of Ageing and Development Journal website
Publication date:
2016-03-05
DOI:
EISSN:
1872-6216
ISSN:
0047-6374
URN:
uuid:b749ff0e-1b7e-4ead-802f-b47c60885ee4
Source identifiers:
609472
Local pid:
pubs:609472

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP