Journal article icon

Journal article

MDM2 SNP309 accelerates colorectal tumour formation in women.

Abstract:

Recent studies have shown that the G-allele of MDM2 SNP309 (T/G) in the p53 tumour suppressor pathway can accelerate tumorigenesis and alter the risk of various cancers in women and not in men. In this report, data are presented from two independent groups of patients that suggest that the G-allele of SNP309 accelerates colorectal tumour formation only in women, and that lend further support to the model that primarily female-specific hormones, such as oestrogen, could either directly or indi...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1136/jmg.2006.043539

Authors


Expand authors...
Journal:
Journal of medical genetics
Volume:
43
Issue:
12
Pages:
950-952
Publication date:
2006-12-05
DOI:
EISSN:
1468-6244
ISSN:
0022-2593
URN:
uuid:b733c14d-7822-4da0-be99-45381da00327
Source identifiers:
69614
Local pid:
pubs:69614

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP