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Why do some primate malarias relapse?

Abstract:
Relapse may have evolved in malaria as a mechanism to avoid suppression by more virulent species in mixed infections, thereby increasing transmission opportunities. Later evolution of long latency in Plasmodium vivax was a necessary adaptation as early hominins moved to colder areas with shorter mosquito breeding seasons. Genetic diversity was maintained through heterologous hypnozoite activation.
Publication status:
In press
Peer review status:
Peer reviewed

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Department:
Oxford, MSD, NDM, Tropical Medicine
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Trends in Parasitology Journal website
Publication date:
2016-08-05
Acceptance date:
2016-08-31
ISSN:
1471-5007
Pubs id:
pubs:647587
URN:
uri:b72ab7ce-d604-48a7-aeab-5e68d8445daf
UUID:
uuid:b72ab7ce-d604-48a7-aeab-5e68d8445daf
Local pid:
pubs:647587

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