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Journal article

Inconsistent trial assessments by the National Institute for Health and Clinical Excellence and IQWiG: standards for the performance and interpretation of subgroup analyses are needed.

Abstract:

OBJECTIVES: The methodology for the critical assessment of medical interventions is well established. Regulatory agencies and institutions adhere, in principle, to the same standards. This consistency, however, is not always the case in practice. STUDY DESIGN AND SETTING: Using the evaluation of the CAPRIE (Clopidogrel versus Aspirin in Patients at risk of Ischemic Events) trial by the British National Institute for Health and Clinical Excellence (NICE) and the German Institute for Quality a...

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Publication status:
Published

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Authors


Hasford, J More by this author
Bramlage, P More by this author
Lehmacher, W More by this author
Einhäupl, K More by this author
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Journal:
Journal of clinical epidemiology
Volume:
63
Issue:
12
Pages:
1298-1304
Publication date:
2010-12-05
DOI:
EISSN:
1878-5921
ISSN:
0895-4356
URN:
uuid:b727823b-a929-4e36-8cbf-22e7cd42de99
Source identifiers:
119554
Local pid:
pubs:119554

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