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Journal article

Effects of fenfluramine, m-chlorophenylpiperazine, and other serotonin-related agonists and antagonists on penile erections in nonhuman primates.

Abstract:

Fenfluramine, m-chlorophenylpiperazine (m-CPP), 1-phenylpiperazine, and the buspirone metabolite, 1-(2-pyrimidyl)piperazine given intravenously to adult rhesus monkeys regularly elicited penile erections. In contrast, serotonin (5-HT) agonists with 5-HT1A site specificity (8-OH-DPAT, buspirone) as well as trazodone, ritanserin, and metergoline were no different from saline in producing penile erections. Fenfluramine's effects were blocked by the 5-HT2 antagonists, ritanserin and metergoline, ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Life sciences
Volume:
43
Issue:
16
Pages:
1297-1303
Publication date:
1988-01-01
DOI:
EISSN:
1879-0631
ISSN:
0024-3205
URN:
uuid:b7029df6-5aaa-482c-90da-9a3c3eec2b52
Source identifiers:
113901
Local pid:
pubs:113901

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