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Journal article

Cholinergic agonism alters cognitive processing and enhances brain functional connectivity in patients with multiple sclerosis.

Abstract:

The aim of this study is to define mechanisms underlying the pharmacological effects of brain cholinesterase inhibition on cognitive function in patients with multiple sclerosis (MS). Both a Stroop task and an N-back task were used to probe the changes in brain activity using functional magnetic resonance imaging (fMRI) in a single (investigator)-blind, crossover treatment design studying 15 patients with multiple sclerosis (12 relapsing remitting, 3 secondary progressive) taking rivastigmine...

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Publication status:
Published

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Publisher copy:
10.1177/0269881108093271

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Matthews, PM More by this author
Journal:
Journal of psychopharmacology (Oxford, England)
Volume:
23
Issue:
6
Pages:
686-696
Publication date:
2009-08-05
DOI:
EISSN:
1461-7285
ISSN:
0269-8811
URN:
uuid:b6fdbdf4-03b5-430d-9fc7-a4d188d37ad2
Source identifiers:
241342
Local pid:
pubs:241342

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