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Challenges in immunisation against bacterial infection in children.

Abstract:

Polysaccharide-encapsulated organisms such as S. pneumoniae, H. influenzae type b and N. meningitidis are the leading causes of serious invasive bacterial diseases and pneumonia in children. The use of conjugate vaccines in developed countries has markedly decreased the burden of disease and mortality from these organisms through direct protection of the immunised and through herd immunity. Although conjugate vaccines are highly immunogenic, antibody levels after immunisation in early infancy...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics, Biomedical Research Centre
Role:
Author
Journal:
Early human development
Volume:
86
Issue:
11
Pages:
695-701
Publication date:
2010-11-05
DOI:
EISSN:
1872-6232
ISSN:
0378-3782
URN:
uuid:b6e629bb-b3a8-4e57-afae-c5e2d20988e5
Source identifiers:
119317
Local pid:
pubs:119317

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