- Abstract:
-
Cognitive facilitation by physostigmine and tetrahydroaminoacridine (THA) was compared in two primate models. Disruption of spatial delayed response performance by scopolamine (0.03 mg/kg) was fully reversed by coadministration of 5 doses of physostigmine in the range 0.03-0.08 mg/kg, but by only one dose (4.0 mg/kg) of THA; partial reversal of some effects of scopolamine was observed at 1 and 3 mg/kg of THA. Visual recognition memory was enhanced following treatment with 4 doses of physostig...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/0197-4580(90)90025-u
-
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- Journal:
- Neurobiology of aging
- Volume:
- 11
- Issue:
- 6
- Pages:
- 609-613
- Publication date:
- 1990
- DOI:
- EISSN:
-
1558-1497
- ISSN:
-
0197-4580
- URN:
-
uuid:b6ccef73-2baf-4628-a459-cc421475c7bf
- Source identifiers:
-
12910
- Local pid:
- pubs:12910
- Language:
- English
- Keywords:
- Copyright date:
- 1990
Journal article
Direct comparison of cognitive facilitation by physostigmine and tetrahydroaminoacridine in two primate models.
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