Journal article icon

Journal article

Direct comparison of cognitive facilitation by physostigmine and tetrahydroaminoacridine in two primate models.

Abstract:

Cognitive facilitation by physostigmine and tetrahydroaminoacridine (THA) was compared in two primate models. Disruption of spatial delayed response performance by scopolamine (0.03 mg/kg) was fully reversed by coadministration of 5 doses of physostigmine in the range 0.03-0.08 mg/kg, but by only one dose (4.0 mg/kg) of THA; partial reversal of some effects of scopolamine was observed at 1 and 3 mg/kg of THA. Visual recognition memory was enhanced following treatment with 4 doses of physostig...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Neurobiology of aging More from this journal
Volume:
11
Issue:
6
Pages:
609-613
Publication date:
1990-01-01
DOI:
EISSN:
1558-1497
ISSN:
0197-4580
Language:
English
Keywords:
Pubs id:
pubs:12910
UUID:
uuid:b6ccef73-2baf-4628-a459-cc421475c7bf
Local pid:
pubs:12910
Source identifiers:
12910
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP