Journal article icon

Journal article

Induction of a striking systemic cytokine cascade prior to peak viremia in acute human immunodeficiency virus type 1 infection, in contrast to more modest and delayed responses in acute hepatitis B and C virus infections.

Abstract:

Characterization of the immune responses induced in the initial stages of human immunodeficiency virus type 1 (HIV-1) infection is of critical importance for an understanding of early viral pathogenesis and prophylactic vaccine design. Here, we used sequential plasma samples collected during the eclipse and exponential viral expansion phases from subjects acquiring HIV-1 (or, for comparison, hepatitis B virus [HBV]or hepatitis C virus [HCV]) to determine the nature and kinetics of the earlies...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1128/jvi.01844-08

Authors


Expand authors...
Journal:
Journal of virology
Volume:
83
Issue:
8
Pages:
3719-3733
Publication date:
2009-04-01
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Source identifiers:
34577
Language:
English
Keywords:
Pubs id:
pubs:34577
UUID:
uuid:b6c0d131-a03f-4f04-af89-1649961ae84f
Local pid:
pubs:34577
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP