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Journal article

Non-viral retinal gene therapy: a review.

Abstract:

In the developed world, diseases of the retina are common causes of untreatable blindness. In many cases, a genetic component to the aetiology has been identified, making the development of gene-based treatments a logical long-term goal. The clinical strategy for retinal gene therapy broadly encompasses two distinct advantages over systemic drug delivery. First is that gene delivery can limit expression of a therapeutic protein to a specific target cell, which is rarely possible even with loc...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Role:
Author
Journal:
Clinical and experimental ophthalmology
Volume:
40
Issue:
1
Pages:
39-47
Publication date:
2012-01-01
DOI:
EISSN:
1442-9071
ISSN:
1442-6404
URN:
uuid:b6a7c34d-b72d-4dad-8aba-aa3acba5f7d1
Source identifiers:
166480
Local pid:
pubs:166480

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