Identification of FOXP1 deletions in three unrelated patients with mental retardation and significant speech and language deficits.

Horn, D; Kapeller, J; Rivera-Brugués, N; Moog, U; Lorenz-Depiereux, B; Eck, S; Hempel, M; Wagenstaller, J; Gawthrope, A; Monaco, AP; Bonin, M; Riess, O; Wohlleber, E; Illig, T; Bezzina, CR; Franke, A; Spranger, S; Villavicencio-Lorini, P; Seifert, W; Rosenfeld, J; Klopocki, E; Rappold, GA; Strom, TM

Abstract:

Mental retardation affects 2-3% of the population and shows a high heritability.Neurodevelopmental disorders that include pronounced impairment in language and speech skills occur less frequently. For most cases, the molecular basis of mental retardation with or without speech and language disorder is unknown due to the heterogeneity of underlying genetic factors.We have used molecular karyotyping on 1523 patients with mental retardation to detect copy number variations (CNVs) including delet...

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APA Style

Horn, D., Kapeller, J., Rivera-Brugués, N., Moog, U., Lorenz-Depiereux, B., Eck, S., Hempel, M., Wagenstaller, J., Gawthrope, A., Monaco, A. P., Bonin, M., Riess, O., Wohlleber, E., Illig, T., Bezzina, C. R., Franke, A., Spranger, S., Villavicencio-Lorini, P., Seifert, W., … Strom, T. M. (2010). Identification of FOXP1 deletions in three unrelated patients with mental retardation and significant speech and language deficits. Human Mutation, 31(11), E1851–E1860.

MLA Style

Horn, D., et al. “Identification of FOXP1 Deletions in Three Unrelated Patients with Mental Retardation and Significant Speech and Language Deficits.” Human Mutation, vol. 31, no. 11, Human mutation, 2010, pp. E1851–E1860.

Chicago Style

Horn, D, J Kapeller, N Rivera-Brugués, U Moog, B Lorenz-Depiereux, S Eck, M Hempel, et al. 2010. “Identification of FOXP1 Deletions in Three Unrelated Patients with Mental Retardation and Significant Speech and Language Deficits.” Human Mutation 31 (11): E1851–E1860.
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