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Journal article : Comment

Towards the rational design of a next-generation dendritic cell vaccine for cancer immunotherapy

Abstract:

As professional antigen presenting cells (APCs) capable of eliciting primary immune responses among naïve T cells, dendritic cells (DCs) offer an attractive target for immune intervention. While some strategies for vaccination have sought to deliver antigens direct to DCs in vivo, others have pulsed DCs with target antigens ex vivo prior to administration. Indeed, numerous clinical studies of cancer immunotherapy have been conducted over the past two decades based on this approach, most of th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.18609/cgti.2021.086

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0002-3057-6866
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Publisher:
Bioinsights Publishing Ltd Publisher's website
Journal:
Cell and Gene Therapy Insights Journal website
Volume:
7
Issue:
5
Pages:
637–650
Publication date:
2021-06-08
Acceptance date:
2021-05-25
DOI:
EISSN:
2059-7800
Language:
English
Keywords:
Subtype:
Comment
Pubs id:
1179218
Local pid:
pubs:1179218
Deposit date:
2021-05-28

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