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Rapid, heterogeneous biocatalytic hydrogenation and deuteration in a continuous flow reactor

Abstract:

The high selectivity of biocatalysis offers a valuable method for greener, more efficient production of enantiopure molecules. Operating immobilised enzymes in flow reactors can improve the productivity and handling of biocatalysts, and using H2 gas to drive redox enzymes bridges the gap to more traditional metal‐catalysed hydrogenation chemistry. Herein, we describe examples of H2‐driven heterogeneous biocatalysis in flow employing enzymes immobilised on a carbon nanotube column, achieving n...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/cctc.202000161

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More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Materials
Role:
Author
Publisher:
Wiley
Journal:
ChemCatChem More from this journal
Volume:
12
Issue:
15
Pages:
3913-3918
Publication date:
2020-06-12
Acceptance date:
2020-04-02
DOI:
EISSN:
1867-3899
ISSN:
1867-3880
Language:
English
Keywords:
Pubs id:
1098454
Local pid:
pubs:1098454
Deposit date:
2020-04-03

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