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Thesis

Investigation of the nascent human transcriptome

Abstract:

High-throughput sequencing of transcripts through RNA-Seq has revolutionised the way gene expression can be understood. However, RNA-Seq only measures the steady-state levels of stably-expressed transcripts rather than the act of transcription. To measure nascent transcription, a range of sequencing methods have been developed, all with a range of different benefits and disadvantages. This study aims to advance the already established transient transcriptome sequencing (TT-Seq) approach an...

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Division:
MSD
Department:
Biochemistry
Role:
Author

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Deposit date:
2020-12-05

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