- Abstract:
-
Multicellular organisms can be regenerated from totipotent differentiated somatic cell or nuclear founders [1-3]. Organisms regenerated from clonally related isogenic founders might a priori have been expected to be phenotypically invariant. However, clonal regenerant animals display variant phenotypes caused by defective epigenetic reprogramming of gene expression [2], and clonal regenerant plants exhibit poorly understood heritable phenotypic ("somaclonal") variation [4-7]. Here we show tha...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.cub.2011.07.002
-
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- Journal:
- Current biology : CB
- Volume:
- 21
- Issue:
- 16
- Pages:
- 1385-1390
- Publication date:
- 2011-08-05
- DOI:
- EISSN:
-
1879-0445
- ISSN:
-
0960-9822
- URN:
-
uuid:b67a4c5a-ef37-482a-8ccf-410f2e8a2668
- Source identifiers:
-
167563
- Local pid:
- pubs:167563
- Copyright date:
- 2011
Journal article
Regenerant Arabidopsis lineages display a distinct genome-wide spectrum of mutations conferring variant phenotypes.
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