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Effect of inhaled prostaglandin E2 on allergen-induced asthma.

Abstract:

Prostaglandin E2 (PGE2) is produced in the lung but unlike most other lipid mediators has potentially important antiallergic effects. Whether these properties are relevant to asthma has not been established. The effect of inhaled PGE2 on allergen-induced asthma was examined in a double-blind crossover study of eight subjects with asthma. In Study 1 subjects inhaled 100 micrograms PGE2 or placebo 5 min before a normal saline challenge, and FEV1 and bronchial reactivity to methacholine was meas...

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Publisher copy:
10.1164/ajrccm/148.1.87

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Journal:
American review of respiratory disease
Volume:
148
Issue:
1
Pages:
87-90
Publication date:
1993-07-01
DOI:
ISSN:
0003-0805
Source identifiers:
435415
Language:
English
Keywords:
Pubs id:
pubs:435415
UUID:
uuid:b674f62b-e835-479f-95cb-90ac3cee3191
Local pid:
pubs:435415
Deposit date:
2013-11-16

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