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Linkage analysis of a candidate region in Scandinavian sib pairs with multiple sclerosis reveals linkage to chromosome 17q.

Abstract:

To date, four genome screens have been completed in the demyelinating autoimmune disease multiple sclerosis (MS). Although these screens failed to identify any loci with major effects on susceptibility, several novel regions of potential linkage were suggested, including the long arm of chromosome 17. In order to further pursue this promising region we have investigated six highly polymorphic microsatellite markers in 115 Scandinavian families with MS affected sib pairs. Multipoint linkage an...

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Publisher copy:
10.1038/sj.gene.6363705

Authors


Madsen, HO More by this author
Hillert, J More by this author
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Journal:
Genes and immunity
Volume:
1
Issue:
7
Pages:
456-459
Publication date:
2000-10-05
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
URN:
uuid:b671e67d-0643-4eb9-8ab0-9743fadf31b2
Source identifiers:
314752
Local pid:
pubs:314752

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