Thesis icon

Thesis

Chemical probing of glycogenesis

Abstract:

The polysaccharide molecule glycogen represents a crucial glucose (and hence energy) storage reserve present in a wide variety of organisms. In eukaryotes, its biosynthesis is initiated by the glycosyltransferase enzyme Glycogenin, which unusually catalyses its own autoglucosylation to form a short maltosaccharide extending from a tyrosine residue. Glycogenin’s privileged position at the heart of carbohydrate metabolism has sparked wide interest in elucidating its catalytic mechanism. Howe...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Department:
Chemistry Research Laboratory
Role:
Author

Contributors

Department:
Chemistry Research Laboratory
Role:
Supervisor
More from this funder
Name:
Engineering and Physical Sciences Research Council
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:b66bd3aa-b195-4dcc-b55f-4e20cdf527eb
Deposit date:
2018-06-29

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP