Journal article
Guiding the folding pathway of DNA origami.
- Abstract:
-
DNA origami is a robust assembly technique that folds a single-stranded DNA template into a target structure by annealing it with hundreds of short 'staple' strands. Its guiding design principle is that the target structure is the single most stable configuration. The folding transition is cooperative and, as in the case of proteins, is governed by information encoded in the polymer sequence. A typical origami folds primarily into the desired shape, but misfolded structures can kinetically tr...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/nature14860
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Authors
Bibliographic Details
- Journal:
- Nature
- Volume:
- 525
- Issue:
- 7567
- Pages:
- 82-86
- Publication date:
- 2015-09-01
- DOI:
- EISSN:
-
1476-4687
- ISSN:
-
0028-0836
- Source identifiers:
-
539958
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:539958
- UUID:
-
uuid:b66000ee-98bc-4ff2-8e93-de00f7c1f557
- Local pid:
- pubs:539958
- Deposit date:
- 2015-11-12
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- Copyright date:
- 2015
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