Induction of depressed mood disrupts emotion regulation neurocircuitry and enhances pain unpleasantness
Background: Depressed mood alters the pain experience. Yet, despite its clear clinical relevance, little is known about the cognitive and neural mechanisms underlying this phenomenon. We tested an experimental manipulation to unravel the interaction between depressed mood and pain. We hypothesized that dysregulation of the neural circuitry underlying emotion regulation is the mechanism whereby pain processing is affected during depressed mood.
Methods: Using functional magnetic reson...Expand abstract
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