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Thesis

Towards real-time antibody-based vital optical imaging of early oesophageal neoplasia

Abstract:

Background: The incidence of oesophageal cancer is rising worldwide, yet the surveillance of patients at risk is very ineffective when using white-light reflectance endoscopy. Overexpression of proteins such as the intracellular enzyme Cyclooxygenase-2 (COX-2) and the tyrosine kinase receptor c-Met has been reported in oesophageal premalignant lesions and adenocarcinomas. The goal of this study is to develop optical imaging probes that target diagnostic biomarkers for the ...

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Institution:
University of Oxford
Oxford college:
Trinity College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:b63c4253-8a3f-4f49-a9ab-cba7305b0f76
Deposit date:
2019-11-20

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