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Prodromal Parkinsonism and neurodegenerative risk stratification in REM sleep behaviour disorder

Abstract:
Objectives. REM sleep behaviour disorder (RBD) is the most specific marker of prodromal alpha-synucleinopathies. We sought to delineate the baseline clinical characteristics of RBD and evaluate risk stratification models. Methods. Clinical assessments were performed in 171 RBD, 296 control and 119 untreated Parkinson’s (PD) subjects. Putative risk measures were assessed as predictors of prodromal neurodegeneration and Movement Disorders Society (MDS) criteria... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/sleep/zsx071

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More from this funder
Name:
National Institute for Health Research
Grant:
Dementias
NeurodegenerativeDiseasesResearchNetwork
More from this funder
Name:
Parkinson's UK
Grant:
Monument Trust Discovery Award
Publisher:
Oxford University Press
Journal:
Sleep More from this journal
Volume:
40
Issue:
8
Article number:
zsx071
Publication date:
2017-05-04
Acceptance date:
2017-03-30
DOI:
EISSN:
1550-9109
ISSN:
0161-8105
Keywords:
Pubs id:
pubs:692439
UUID:
uuid:b638ed4d-ea4f-4cd2-b6cd-9b39df42218f
Local pid:
pubs:692439
Deposit date:
2017-05-05

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