Journal article
Identification of a clonally restricted 90 kD heterodimer on two human cloned natural killer cell lines. Its role in cytotoxic effector function.
- Abstract:
-
The present studies were carried out to identify surface molecules involved in the cytotoxic effector function of a human natural killer (NK) clone termed JT9. This clone represents a mature T lymphocyte (T3+T8+T11+) mediating NK-like activity. Using JT9 for immunization, one monoclonal antibody termed anti-NKTa was selected that blocked the cytotoxicity of the clone towards K562 cells. Reactivity of anti-NKTa antibody was assessed using a large panel of lymphoid and nonlymphoid cells includi...
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- Publication status:
- Published
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- Publisher copy:
- 10.1084/jem.158.5.1547
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Authors
Bibliographic Details
- Journal:
- Journal of experimental medicine
- Volume:
- 158
- Issue:
- 5
- Pages:
- 1547-1560
- Publication date:
- 1983-11-01
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- Source identifiers:
-
24720
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:24720
- UUID:
-
uuid:b637dc61-22bd-479a-a436-dff332ce0fd6
- Local pid:
- pubs:24720
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1983
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