- Abstract:
-
The bioenergetic state of 15 human tumours was examined with phosphorus-31 magnetic resonance spectroscopy. A striking diversity in metabolic patterns was observed, and significant differences from normal tissue were seen in all cases. A common feature was an elevation of intracellular pH, which may be related to an increase in Na+/H+ exchange during cell activation. It is unlikely that the patterns observed directly correlate with malignancy, but characterisation of the energetic state of a ...
Expand abstract - Publisher copy:
- 10.1016/s0140-6736(86)92558-4
-
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- Journal:
- Lancet
- Volume:
- 2
- Issue:
- 8497
- Pages:
- 8-11
- Publication date:
- 1986-07-05
- DOI:
- EISSN:
-
1474-547X
- ISSN:
-
0140-6736
- URN:
-
uuid:b608b17c-cd4f-414c-90e7-ab7d41f1bbfb
- Source identifiers:
-
248114
- Local pid:
- pubs:248114
- Copyright date:
- 1986
Journal article
Biochemical investigation of human tumours in vivo with phosphorus-31 magnetic resonance spectroscopy.
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