Journal article icon

Journal article

Ion channel structures: a review of recent progress.

Abstract:

Several ion channel structures have recently been determined, including MthK (a bacterial K+ channel in an open state), KirBac (a bacterial homolog of mammalian inward rectifier K+ channels), KvAP (a bacterial voltage-activated K+ channel) and the pore domain of the nicotinic acetylcholine receptor. Analysis of these structures has increased our understanding of the molecular mechanisms underlying channel gating. A hydrophobic gate appears to operate in a number of channels. Structures of lig...

Expand abstract
Publication status:
Published

Actions


Authors


Journal:
Current opinion in drug discovery and development
Volume:
6
Issue:
5
Pages:
611-619
Publication date:
2003-09-01
EISSN:
2040-3437
ISSN:
1367-6733
Source identifiers:
100997
Language:
English
Keywords:
Pubs id:
pubs:100997
UUID:
uuid:b6081fcc-f890-4d95-9b77-b96a791119da
Local pid:
pubs:100997
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP