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Bacteriophage P23-77 capsid protein structures reveal the archetype of an ancient branch from a major virus lineage.

Abstract:

It has proved difficult to classify viruses unless they are closely related since their rapid evolution hinders detection of remote evolutionary relationships in their genetic sequences. However, structure varies more slowly than sequence, allowing deeper evolutionary relationships to be detected. Bacteriophage P23-77 is an example of a newly identified viral lineage, with members inhabiting extreme environments. We have solved multiple crystal structures of the major capsid proteins VP16 and...

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Publication status:
Published

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Publisher copy:
10.1016/j.str.2013.02.026

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
Journal:
Structure (London, England : 1993) More from this journal
Volume:
21
Issue:
5
Pages:
718-726
Publication date:
2013-05-01
DOI:
EISSN:
1878-4186
ISSN:
0969-2126
Language:
English
Keywords:
Pubs id:
pubs:405025
UUID:
uuid:b6081234-550d-400d-9400-4336e7d25e8e
Local pid:
pubs:405025
Source identifiers:
405025
Deposit date:
2013-11-17

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