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Physical activity of UK adults with chronic disease: cross-sectional analysis of accelerometer-measured physical activity in 96 706 UK Biobank participants

Abstract:
Background Physical inactivity is associated with an increased risk of major chronic diseases, however uncertainty exists about which chronic diseases, themselves, might contribute to physical inactivity. The objective of this study was to compare the physical activity of those with chronic diseases to healthy individuals using an objective measure of physical activity.

Methods We conducted a cross-sectional analysis of data from 96 706 participants aged 40 years or older from the UK Biobank prospective cohort study (2006 – 2010). Diagnoses were identified through ICD 9 and 10 coding within hospital admission records and cancer registry linked to UK Biobank participants. We extracted summary physical activity information from participants who wore a wrist-worn triaxial accelerometer for seven days. Statistical analyses included computation of adjusted geometric means and means using general linear models.

Results Participants with chronic disease undertook 9% or 61 minutes (95% confidence interval [CI]: 57.8-64.8) less moderate activity and 11% or three minutes (95% CI: 2.7-3.3) less vigorous activity per week than individuals without chronic disease. Participants in every chronic disease subgroup took less physical activity than those without chronic disease. Sixty-seven diagnoses within these subgroups were associated with lower moderate activity.

Conclusions The cross-sectional association of physical activity with chronic disease is broad. Given the substantial health benefits of being physically active, clinicians and policymakers should be aware that their patients with any chronic disease are at greater health risk from other diseases than anticipated because of their physical inactivity.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ije/dyy294

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author


Publisher:
Oxford University Press
Journal:
International Journal of Epidemiology More from this journal
Volume:
48
Issue:
4
Pages:
1167–1174
Publication date:
2019-02-05
Acceptance date:
2018-12-19
DOI:
EISSN:
1464-3685
ISSN:
0300-5771


Keywords:
Pubs id:
pubs:953429
UUID:
uuid:b60507c9-5a9f-4c73-bbb4-fb5d643e676c
Local pid:
pubs:953429
Deposit date:
2018-12-19

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