Off-pump or on-pump coronary-artery bypass grafting at 30 days.

Journal article

BACKGROUND: The relative benefits and risks of performing coronary-artery bypass grafting (CABG) with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary bypass (on-pump CABG), are not clearly established. METHODS: At 79 centers in 19 countries, we randomly assigned 4752 patients in whom CABG was planned to undergo the procedure off-pump or on-pump. The first coprimary outcome was a composite of death, nonfatal stroke, nonfatal myocardial infarction, or new renal fail...

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Authors: Lamy, A; Devereaux, P; Prabhakaran, D; Taggart, D; Hu, S

• Publication status: Published
• Journal: New England journal of medicine
• Volume: 366
• Issue: 16
• Pages: 1489-1497
• Publication date: 2012-04-01
• DOI: 10.1056/nejmoa1200388
• EISSN: 1533-4406
• ISSN: 0028-4793
• Language: English
• Keywords: Postoperative Complications; Renal Insufficiency; Male; Aged; CORONARY Investigators; Humans; Coronary Artery Bypass; Coronary Artery Disease; Reoperation; Blood Transfusion; Stroke; Middle Aged; Treatment Outcome; Myocardial Infarction; Coronary Artery Bypass, Off-Pump; Single-Blind Method; Female