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Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity.

Abstract:

RATIONALE: MDMA is a popular drug of abuse in adolescents which causes serotonergic neurotoxicity in adult but not young rodents. However, few studies have examined the long-term behavioural consequence of MDMA and it is unclear whether such changes occur in the absence of neurotoxicity. OBJECTIVES: The present study examined whether treatment of young rats with MDMA produced long-term behavioural alterations without accompanying serotonergic neurotoxicity. METHOD: Male Lister hooded rats ( n...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-001-0931-z

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Journal:
Psychopharmacology
Volume:
159
Issue:
4
Pages:
437-444
Publication date:
2002-02-01
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
Source identifiers:
222952
Language:
English
Keywords:
Pubs id:
pubs:222952
UUID:
uuid:b5efd6d5-58bd-49bb-a255-7a6d02427f49
Local pid:
pubs:222952
Deposit date:
2012-12-19

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