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Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis

Abstract:

Vitamin D has biological effects on multiple knee joint structures and data from observational studies suggest vitamin D deficiency may be linked with pain and progression of knee OA. In the UK VIDEO study, a multicentre 3-year randomised placebo controlled trial of vitamin D therapy (800 IU/day) in patients with symptomatic knee OA, there was no evidence of an effect of vitamin D therapy on either pain or structural progression of disease as assessed using x-rays. We hypothesised, however, t...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.joca.2018.02.613

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Publisher:
Elsevier Publisher's website
Volume:
26
Issue:
S1
Pages:
S118
Publication date:
2018-04-16
Acceptance date:
2018-01-08
DOI:
Pubs id:
pubs:856201
URN:
uri:b5e95bbd-c2c4-4a5c-8ecf-8015bfe18717
UUID:
uuid:b5e95bbd-c2c4-4a5c-8ecf-8015bfe18717
Local pid:
pubs:856201

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