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Journal article

Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration.

Abstract:

In the age of stem cell engineering it is critical to understand how stem cell activity is regulated during regeneration. Hairs are mini-organs that undergo cyclic regeneration throughout adult life, and are an important model for organ regeneration. Hair stem cells located in the follicle bulge are regulated by the surrounding microenvironment, or niche. The activation of such stem cells is cyclic, involving periodic beta-catenin activity. In the adult mouse, regeneration occurs in waves in ...

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Publication status:
Published

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Publisher copy:
10.1038/nature06457

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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
Journal:
Nature More from this journal
Volume:
451
Issue:
7176
Pages:
340-344
Publication date:
2008-01-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Language:
English
Keywords:
Pubs id:
pubs:12628
UUID:
uuid:b5e435a9-e8c2-4425-877f-32788cb1dd04
Local pid:
pubs:12628
Source identifiers:
12628
Deposit date:
2012-12-19

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